Researchers at Germany's University of Konstanz have established a fluorescence-based method for screening small molecules to identify potential antimicrobial agents. Using the Freedom EVO® workstation’s MultiChannel Arm™ 384, the University’s Screening Center has developed an innovative technique allowing reliable liquid transfers down to 80 nanoliters.
Scientists working in the Screening Unit at the Institute for Molecular Pharmacology in Germany are finding the low volume pipetting capability of the MultiChannel Arm™ 384 beneficial for the investigation of siRNAs and small molecule compound screening.
The Novartis Animal Health Research Center has invested in an automated compound logistics system to aid drug discovery, taking advantage of the exceptional pipetting capabilities of the MultiChannel Arm™ 384.
High throughput screening for drug discovery depends on reliable liquid handling, like that provided by Tecan’s Freedom EVO® platform. Chicago-based company SAMDI Tech has automated its proprietary label-free SAMDI technology on a Freedom EVO system for performing rapid and quantitative analysis of challenging biochemical targets.
Production of dose-response plates and cherry-picking are essential steps in early drug discovery to enable testing of many thousands of compounds. Researchers at Novartis are benefitting from the automated plate generation capabilities of two customized systems based on Freedom EVO® 200 platforms, each equipped with an MCA 384, significantly increasing sample throughput to over 10,000 compounds a day.