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Endocrinology

We provide you with a comprehensive portfolio of highly sensitive, reliable immunoassays for measuring steroids, peptides, proteins and amino hormones from a variety of sample matrices. They can overcome the disadvantages of working with radioactivity without the need for huge investments. This is especially interesting to departments that have no access to MS equipment. Numerous studies have shown that most of our assays correlate strongly to LC-MS/MS and RIA.




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Tab 01 / Application fields
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Gynecology, Andrology, ivF

Gynecology covers health-related aspects of the female reproductive system; its male counterpart is andrology.

In vitro fertilization (IVF) is a common treatment modality for infertility when other methods of assisted reproductive technology have failed.

We provide high quality assays for measurement of e.g. 17-OH-Progesterone (17-OH-P), 5alpha-Dihydrotestosterone (DHT), Estrone (E1).

Endocrinology

Influence of Congenital Adrenal Hyperplasia (CAH) on the hormones in the body system. Due to enzyme deficiency the production of Cortisol and Aldosterone is decreased and elevated values of 17-OH-P are measured in serum or plasma. 17-OH-P represents one of the most suitable biochemical marker for the diagnosis of CAH.

Hypertension
Renin-Angiotensin System

Hypertension

Hypertension is a cardiac chronic medical condition in which systemic arterial blood pressure is elevated. Persistent hypertension is a significant risk factor for strokes, heart attacks, heart failure, and arterial aneurysm, and is leading cause of chronic renal failure.

We offer assays for routine diagnostics and research purposes in the area of Hypertension and its initial reasons.

Tumor markers

Tumor markers ELISAs are also part of our broad portfolio for routine diagnostics, clinical research and therapy follow-up.

Some tumor markers are specific for a single type of cancer, while others can be found in many types of cancer.

Bone and mineral metabolism

Dysfunction of the Vitamin D and parathyroid hormone (PTH) pathways are usually indicators of diseases involving acalcinosis (too little calcium) or calcium excess. Typically, these are Hypo- and Hyperparathyreodism and kidney calcification. Especially, patients already having kidney problems are at high risk. As such the determination of a patient’s vitamin D and PTH levels are essential to the correct therapeutic intervention.

Metabolic Syndrome

Metabolic syndrome is associated with several medical conditions typically associated with “western lifestyle” such as obesity or a disturbed lipoprotein (fat) metabolism. All these conditions can lead to developing cardiovascular diseases, gastrointestinal diseases or even diabetes type II. Again a deficiency in Vitamin B12 will lead to effects on our central nervous system and is associate i.e. with fatigue, anemia and even depression.

Growth hormones

The measurement of insulin-like growth factor-I (IGF-I) and Insulin-like Growth Factor Binding Protein 3 (IGFBP-3) in serum or plasma is of especially high utility in the diagnostic work-up of growth disturbances, particularly with regard to human growth hormone (hGH) deficiency or acromegaly.

Thyroid Function

Thyroid function tests (TFTs) are amongst the most commonly requested laboratory investigations in the world. Most TFTs are effective at interpretation and confirmation of the clinical picture of euthyroidism, hypothyroidism or hyperthyroidism. However, thyroid function testing becomes problematic when the tests are performed in patients who have any significant co-existing illness.




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Tab 02 / Literature
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ELISA

Selected ELISA reagents from our wide range of products for your Freedom EVOlyzer.

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ELISA for your ThunderBolt

Selected ELISA reagents from our wide range of products for your ThunderBolt.

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Find here selected products. Protocols for application support are available. The combined use of assays, process script and open system instrument (e.g. EVOlyzer®, ThunderBolt®) has to be validated individually on site by each laboratory. Interchangeability is only valid within same lot numbers for the single components.