April 21, 2020
Maurano MT, Ramaswami S, Westby G, Zappile P, Dimartino D, Shen G, Feng X, Ribeiro-dos-Santos AM, Vulpescu NA, Black M, Hogan MS, Marier C, Meyn P, Zhang Y, Cadley J, Ordoñez R, Luther R, Huang E, Guzman E, Serrano A, Belovarac B, Gindin T, Lytle A, Pinnell J, Vougiouklakis T, Boytard L, Chen J, Lin LH, Rapkiewicz A, Raabe V, Samanovic-Golden MI, Jour G, Osman I, AgueroRosenfeld M, Mulligan MJ, Cotzia P, Snuderl M, Heguy A
SARS-CoV-2 is being studied on a global scale to understand its evolution, spread and impact on human health. Maurano et al. from New York University School of Medicine successfully performed large scale genomic surveillance in the NYC metropolitan area from 236 patient samples (Nasopharyngeal swabs). The researchers at NYU chose Trio RNA-Seq for its robust performance with degraded and low viral titer samples. The results from this publication indicated that there was undetected community spread and concluded that the major strains for the outbreak originated in Europe.