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Tecan offers a variety of sophisticated solutions for protein analysis. From robust multimode readers to the integrated label-free analysis using the FortéBio Octet® platform to protein digestion and MALDI spotting, we can streamline your assay development process.
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Tab 01 / Detection
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Tecan’s microplate readers enable protein quantification and analysis at the touch of a button, and can be easily integrated in liquid handling platforms. Multimode readers offer a choice of detection modes to suit individual needs, with a modular design allowing them to be upgraded as laboratory needs change.
Show moreThe Infinite® 200PRO is our most popular instrument for protein detection and analysis.
Exceptional format flexibility and fast read times
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Tab 02 / Label-free
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Empower your biotherapeutic development and drug discovery with Tecan and FortéBio – automated high throughput Dip and Read™ biosensor assays using the Octet® platform.
Fully automate sample and assay preparation, to allow label-free, real-time interaction analysis in 96- and 384-well microplate formats.
Show more…and more
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Tab 03 / maldi
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The Freedom EVO® Protein Digest workstation enables fully automated protein digestion for subsequent MALDI-TOF analysis, including destaining of gel plugs, reduction, alkylation, in-gel trypsin digestion, peptide extraction and spotting onto MALDI targets. The system allows up to 192 samples to be processed a day, including MALDI spotting.
Show moreBoth automated and manual in-gel digest protocols need approximately one hour of preparation (green bar), but automation frees the user from additonal hands-on time (red bars) over a seven hour period.
Data kindly provided by Max-Planck-Institute of Experimental Medicine in Göttingen, Germany (see Jahn et al., Anal. Bioanal. Chem. 2006, 386:92-103)
Eliminating salt from peptide samples obtained from 1D- or 2D-gel protein digestion is essential for successful MS analysis.
Fully automated peptide desalting and MALDI target spotting using ZipTip® columns (Merck) on Tecan liquid handling platforms. Various sizes of MALDI targets from different manufacturers can be accommodated, allowing high throughput, error-free spotting.
Highlights
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Tab 04 / Literature
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The proteomics group at the Institute for Systems Biology, Seattle, is using a Freedom EVO to generate samples for analysis by mass spectrometry, providing the reproducibility and throughput to enable a range of different projects to be run entirely in house.
Scientists at the Center for Integrated Protein Science Munich have taken advantage of the 3D scanning capabilities of the Infinite® M1000 microplate reader for the study of epigenetics.
Integration of the FortéBio Octet® 384 platform on the Freedom EVO® workstation offers automated, real-time, label-free assays to support bioprocessing and drug discovery workflows. This robust, off-the-shelf integration provides automated liquid handling for assay plate set-up and increases walkaway times.
The Proteomics Group at the Max Planck Institute, Göttingen, has collaborated with Tecan to develop an innovative automated solution for in-gel digestion in large-scale proteome analyses.