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NGS applications

NGS technologies are transforming life science research and enabling scientists to gain a large wealth of information. Tecan’s proprietary technologies enable researchers to simplify their workflows and gain more information with each sequencing run thus saving time and money. Learn more about the research that is being done globally with Tecan’s NGS products.




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Tab 01 / Cancer
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Transforming disease:
Cancer research made simple

Next-generation sequencing (NGS) technologies are transforming the field of cancer, detection and diagnostic research due to the wealth of genetic information obtained through different sequencing approaches.

Targeted resequencing for mutation detection and RNA-Seq for gene fusion identification and detection are some of the areas where NGS methods have offered technology advantages.

Tecan’s broad portfolio of innovative DNA and RNA library preparation systems provides unique solutions for research into mutation detection and oncology.

Disease progression: Understanding different outcomes Disease progression: Understanding different outcomes

Disease progression: Understanding different outcomes

Dr. Shain and coworkers take an evolutionary look at order of occurrence of pathogenic mutations in melanoma. Their research looks at 37 FFPE samples and 293 cancer relevant genes with DNA prepared using the Ovation® Ultralow Library System. Their work characterizes the series of genetic alternations that occur during melanoma progression to define the trajectory of different melanoma subtypes.

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Exome approach: Identifying treatment targets Exome approach: Whole Exome Sequencing

Exome approach: Identifying treatment targets

Whole exome sequencing (wgs) only covers protein-coding genes, approximately 3 % of the whole genome. However, it is these protein-coding genes that harbor the majority of genetic variations associated with human diseases. Thus, exome sequencing provides many of the benefits of wgs, while greatly reducing sequencing costs and time. Combining Celero EZ DNA-Seq library prep with exome enrichment provides several key advantages – including a single bead cleanup step – simplifying the workflow and saving cost and time.  

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Tumor immunotherapy: Guidance by RNA-Seq Tumor immunotherapy: Guidance by RNA-Seq

Tumor immunotherapy: Guidance by RNA-Seq

In this publication, Koyama, Akbay, and Li et. al. study the development of resistance to tumor immunotherapy using mouse models of lung adenocarcinoma and define biomarkers associated with adaptive resistance to PD-1 blockade. The team use the Ovation® Universal RNA-Seq System to further their research in T cells and immunotherapy-resistant and untreated tumors.

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Tab 02 / Infectious Disease
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Tab 03 / Liquid Biopsy
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Tab 04 / Agrigenomics
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Tab 05 / Microbiomics
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Tab 06 / Epigenetics
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