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AC Extraction Plate™

The AC Extraction Plate speeds up your sample prep routine, and is a perfect match to our Freedom EVO and Fluent liquid handling platforms.

It simplifies your LC-MS sample prep routine for apolar small molecules, such as vitamin D, certain therapeutic drugs and testosterone.
Quality and reliability
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Tab 01 / Quality and reliability
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Workflow and benefits

The AC Extraction Plate with TICE™ (Tecan Immobilized Coating Extraction) technology revolutionizes your sample preparation routine. A simple pipette and shake sequence is all that is required, with no filtration, centrifugation or solvent evaporation steps.

The AC Extraction Plate is easily integrated into automated processes, making it a perfect match for Freedom EVO and Fluent liquid handling platforms.

Key Benefits

COST-EFFECTIVE

Simple pipette and shake workflow, without labor intensive centrifugation, filtration and solvent evaporation steps.

CONVENIENT AND FAST

Just unpack and start, no conditioning or other preparations needed. The sample prep routine is finished after 30-35 min.

HIGHLY REPRODUCIBLE

Pipette and shake routines are easily standardized and automated on a liquid handling platform, eliminating random errors and increasing consistency of results.

QC Kit Progress




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Tab 02 / Videos
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AC Extraction Plate

Presentation of the AC Extraction Plate and visualization of the step-by-step sample extraction process.

Using the AC Extraction Plate with the Freedom EVO and TouchTools™

Easy automation of the AC Extraction Plate on a Freedom EVO liquid handling platform. Clear instructions and information are provided by the TouchTools interface during the sample preparation process.

AC Extraction Plate – Interview at Analytica 2014

Explanation of the benefits of the AC Extraction Plate, and how this can help the customers to simplify their sample prep routines for apolar small molecules.

Clozapine therapeutic drug monitoring at King’s College Hospital London

A senior clinical scientist explains how the AC Extraction Plate has helped them to save time and costs for the analysis of clozapine.




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Tab 03 / Literature
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Brochures

AC Extraction Plate - Sample preparation for LC-MS made easy

This brochure explains the technology behind the AC Extraction Plate, and outlines why this product is unique.

Consumables overview

Reliable assay results and maximized productivity with Tecan’s quality consumables.

White Paper

Technical Background to the Tecan AC Extraction Plate

This white paper explains in detail the technology of the AC Extraction Plate, providing information on the extraction steps and showing which analytes it can be used for. It also contains a Q&A section.

Application Notes

A simple procedure for the extraction of antidepressants from whole blood for LC-MSMS analysis

This application note shows how antidepressants were quantified from whole blood, using samples spiked with standards and authentic samples from impaired drivers.

Estradiol – Simple Sample Preparation Procedure for Quantitative Analysis by LC-MS/MS

Application note showing how the AC Extraction Plate can be used for the quantification of estradiol from serum samples.

Sample preparation with the AC Extraction Plate: extraction of urinary THC metabolites for LC-MSMS quantification

In this application note describes a method for sample prep and quantitative analysis of THC from urine.

Quantitative Determination of Serum 25-OH-vitamin D3/D2 using the Tecan AC Extraction Plate ™ and the Bruker amaZon speed Ion Trap (LCMS-95)

In this application note, a method for sample prep and quantitation of 25-OH-vitamin D is presented.

Automated sample preparation for the determination of testosterone in serum by LC-MSMS

An automated method for the determination of testosterone in serum by LC-MS using a Freedom EVO liquid handling platform is presented.

Automated Sample Preparation of 25-OH-Vitamin D3/D2 from Serum with the Tecan Freedom® EVO

An application note describing a method for automated sample preparation for vitamin D analysis on the Freedom EVO liquid handling platform.

A unique sample preparation method for the extraction of ibuprofen from urine for LC-MSMS quantification

The application note presents a method for sample prep and quantitation of the painkiller ibuprofen in pig urine.

Simple sample preparation for the determination of vitamin D in serum by LC-MS/MS

This application covers a method for sample prep and LC-MS quantification of Vitamin D with the AC Extraction Plate. Day-to-day variability is also investigated and documented.

Technical Notes

Simplified method development with the AC Extraction Plate

A technical description of how the AC Extraction Plate simplifies sample preparation, and which types of analytes this product is particularly suitable for.

Effectiveness of the AC Extraction Plate for protein removal

This technical note presents evidence that the extracts from the AC Extraction Plate are free of proteins.

Extractables do not affect downstream vitamin D analysis by LC-MS/MS

This technical note shows that extractables, which potentially come from labware, have no influence on vitamin D analysis by LC-MS with respect to ion suppression

Using the Tecan AC Extraction Plate for sample preparation - A screening study

In this technical note, a preliminary screening of several dozen analytes is performed, and the outcome is discussed on the basis of structure-activity relationships

Ensuring reproducible extraction performance through routine quality control

This technical note describes quality control procedures in detail.

Posters

Simple extraction of antidepressants from whole blood for LC-MSMS analysis using coated well plates

Poster displaying the results of using the AC Extraction Plate for extraction and LC-MSMS analysis of anti-depressants

Sample preparation of multiple steroids for quantitative determination by LC-MS/MS – comparison of two extraction procedures

Poster comparing the AC Extraction Plate with another commercially available consumable for the extraction of multiple steroids in one run.

1,25-di-hydroxy Vitamin D analysis by LC-MS: Optimization for sample prep automation and medium throughput lab

Poster presenting the results for automated sample prep and LC-MS quantification of vitamin D.

Rapid, fully-automated plasma Clozapine and NOR-Clozapine analysis using Tecan AC Extraction Plate technology and isotopic internal calibration MS/MS

Poster describing how the AC Extraction Plate and the Freedom EVO liquid handling platform can be used for therapeutic drug monitoring of clozapine.

Estradiol - Investigation of two Sample Preparation Procedures for Quantitative Analysis by LC-MS/MS

This poster compares two different sample prep procedures for estradiol.

Easy to automate extraction of THC-metabolites for LC-MS/MS analysis (Ameritox)

This poster presents an automated method for the extraction and quantification of THC metabolites for LC-MS

Automated Sample Preparation of Biological Fluids for LC-MS/MS Analysis

This poster describes how the AC Extraction Plate can be automated on a Freedom EVO liquid handling platform.
Products
Freedom EVO series

Unlimited options, individual solutions - one reliable platform

Fluent series

Simplify your lab with industry-leading application focused automation

Brochures
Applications
For research use only.
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